Effi cacy of Panax Ginseng Meyer Herbal Preparation HRG80 in Preventing and Mitigating Stress-Induced Failure of Cognitive Functions in Healthy Subjects: A Pilot, Randomized, Double-Blind, Placebo-Controlled Crossover Trial.
Mariage PA, Hovhannisyan A, Panossian AG. Pharmaceuticals 2020. 13;57
The aim of this pilot study was to compare the efficacy of hydroponically cultivated red Panax ginseng Meyer root preparation (HRG80) and traditionally harvested six-year-old white P. ginseng standard preparation (PGS) with placebo in relieving symptoms of stress.*^
The effects of HRG80, PGS, and placebo capsules were studied in 50 tired healthy subjects in a three-arm, randomized, double-blinded, placebo-controlled crossover trial. Efficacy-outcome measures included the accuracy of processing the d2 test for cognitive functions, obtained accuracy score in a computerized memory test, and the perceived-stress (PS) score.
A statistically significant interaction effect between time and treatment (p < 0.0001) was observed in the attention d2 and memory tests, indicating that HRG80 treatment was more beneficial than that with a placebo. The effects of PGS were better than those of the placebo, but the difference was not statistically significant. There was significant difference between the effects of HRG80 and PGS (p < 0.0001) that were observed after single (Day 1) and repeated administrations on Days 5 and 12 of treatment.
Overall, HRG80 treatment was significantly superior compared to that with the PGS and placebo regarding attention, memory, and PS scores after single and repeated administrations for 5 and 12 days.*
WHAT THIS MEANS FOR YOU:
• Stay sharp all day long
• Overcome occasional stress
• HRG80 Red Ginseng can help you stay alert,
focused, and energized—even after a long day.*
According to a Gallup poll, 79 percent of Americans are stressed in some way—that’s about 8 out of 10 people. Perhaps you’re one of them. Over time, that stress^ has a depleting effect on daily energy levels, focus, and overall quality of life.
Fortunately, HRG80 Red Ginseng can help. This two-week clinical study compared
HRG80 Red Ginseng, a leading white ginseng supplement from Europe, and a placebo. This was a crossover clinical study, so all participants were subjects in all three study arms.
The people in this study had high levels of occupational stress. They worked in social services, or as tele-operators, engineers, and IT personnel, frequently overloaded with cognitive tasks and exposed to workplace and social demands. That is why attention and accuracy was one of the main focuses of the study.
Participants took a standardized, timed test that assessed and compared their ability to focus and concentrate in the morning, and in the afternoon.
These results are not surprising. Compared to every other ginseng available, HRG80 Red Ginseng is unique. It is hydroponically grown and carefully cultivated in such a way that concentrates its most valuable compounds, called noble ginsenosides. These ginsenosides are 17 times better absorbed† than classic ginsenosides, and HRG80 has seven times more of them than conventional ginseng.
This study shows that if you’d like better support for attention and mental endurance, HRG80 Red Ginseng can help. In very little time, people in this study noticed a difference in how it helped them overcome occasional stress to stay resilient, focused, and energized—results everyone can appreciate!*
The attention score for the placebo group decreased to 11 points below the baseline level. The HRG80 group’s attention score showed a significant difference as it bumped to 5 points above baseline, with positive results starting on the first day. Plus, HRG80 Red Ginseng continued to support attention and focus into the afternoon hours, when the leading white ginseng’s power began to fade.*
†Compared to classic ginsenosides in an in-vitro scientifi c (Caco-2) study
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THESE PRODUCTS ARE NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE